Uremia "relationship" to the body

Many patients with renal insufficiency often do not know what the symptoms of uremia, negligence causing vomiting and other symptoms, resulting in exacerbations. So, what symptoms should consider the uremia it?

Uremia is the general term for a series of symptoms of advanced renal failure occurred. Mainly reflected the symptoms associated with chronic renal failure and symptoms of uremia poisoning and kidney hormone-induced reduction of harmful substances accumulate anemia combined bone occurred. The most common early symptoms of uremia are nausea, vomiting, loss of appetite and other gastrointestinal symptoms. After entering the late stage uremia symptoms of uremia will be manifested in the body system disorders, heart failure, psychosis, coma and other serious cases, life-threatening.
In uremia, in addition to the water, electrolyte, acid-base balance disorders, anemia, bleeding tendency, hypertension aggravated, but also clinical manifestations of each organ system dysfunction, and metabolic disorders caused by physical symptoms of uremia can be divided as follows:
Nervous system (a) uremic symptoms
Neurological symptoms are the main symptoms of uremia. In the early uremia, patients often have dizziness, headache, fatigue, comprehension and memory loss and other symptoms. As the disease worsens, there may be irritability, muscle tremor, convulsions; may eventually develop into apathy, lethargy and coma. These symptoms occur with the following factors: ① some accumulation of toxic substances may cause nerve cell degeneration; ② electrolyte and acid-base balance disorders; ③ renal hypertension caused by cerebral vasospasm, hypoxia and capillary permeability increased, which can cause degeneration of brain cells and brain edema.
Digestive performance (two) uremic symptoms
The earliest symptoms of uremia uremic patients digestive system is loss of appetite or indigestion; exacerbations can occur when anorexia, nausea, vomiting or diarrhea. These symptoms may occur with uremia intestinal bacterial urease to break down urea into ammonia, ammonia stimulate gastrointestinal mucosa causing inflammation and multiple superficial small ulcers and so on. Uremic patients often complicated by gastrointestinal bleeding. Also nausea, vomiting, and also related to the central nervous system dysfunction.
Cardiovascular system performance (three) uremic symptoms
Chronic renal failure and uremia due to renal hypertension, acidosis, hyperkalemia, sodium and water retention, the role of toxic substances such as anemia and heart failure can occur, such as arrhythmias and myocardial damage. Since urea (possibly uric acid) of stimulation effect, but also aseptic pericarditis, patients determined before the pain; smell and pericardial friction rub physical examination. Severe pericardial cavity cellulose and bloody exudate appears. This is uremic symptoms in the cardiovascular system performance.
Respiratory system performance (four) uremic symptoms
Uremic acidosis in patients with slow and deep breathing, severe acidosis can be seen particularity Kussmaul breathing. The off gas exhaled by the patient with Niaowei, which is due to bacterial decomposition of urea solution formed sleeping ammonia sake. Can occur in patients with severe pulmonary edema, or pulmonary calcification cellulose pleurisy and other diseases, pulmonary edema and heart failure, hypoalbuminemia, sodium and water retention and other factors related to the role of stay. Cellulose pleurisy is caused by inflammation of urea stimulation; lung calcification calcium phosphate deposition in the lung tissue caused.
(Five) uremic symptoms on the skin manifestations
Uremic pruritus is common in patients with symptoms that may be toxic products stimulate receptors on the skin caused; others believe and secondary hyperparathyroidism related, because the removal of the parathyroid, can relieve the pain immediately symptoms. In addition, patients with dry skin, scaling and was brown. Changes in skin color, previously thought to be an increase in the urinary pigment so, but check with the absorption spectrophotometer proved mainly for skin pigment melanin. Exposed parts of the skin, can cause slight contusion skin ecchymosis. Since sweat contains high concentrations of urea, and therefore the opening of the sweat glands in the white crystals of urea, known as urea cream.
Related kidney hospital experts said, uremia addition to the above symptoms, there are a variety of clinical disorders, metabolism characterization. In addition, experts suggest that patients with chronic renal insufficiency must concept note of the early symptoms of uremia, early treatment